Never had the patience to 'get' the Blender UI.* I used to get
   involved in UI flame wars on Usability and computer-human
   interaction forums years ago and when I see Blender's mess (even
   their updated UI, which is definitely an improvement to earlier
   versions), i start thinking of ALL THE WAYS they could improve
   the UI, start reorganizing it in my brain, and then get angry
   that such a powerful and useful program has it's own special UI,
   which would be fine if ... ...ok, I'm starting a rant :P**
   Anyway, that always ends up being a distraction from me learning
   Blender.* It's stupid really.* But I get the reaction when I see
   stupid UI mistakes or tricks or games online too... ok, I'm
   going to settle down now :P Im ok, Im ok I'm ok :P You learned
   it.* It's learnable and there's probably some great benefits to
   the layout.* It strikes me as a primarily "key-stroke"
   interface, so once you learn the keystrokes, you'd good to go.*
   I guess I just don't 'feel like it' and all this rant is just a
   coverup for my own laziness :)